学術論文・エビデンス

最終更新日:2018年4月

NEW

2017.10.26 〜 10.27 開催

日本歯科保存学会平成29年度秋季学術大会(147回)

DNAチップを用いた唾液中の歯周病関連細菌叢の評価

山和人、笹部奈津季、船橋英利、熊谷知弘

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NEW

2017.9.22 〜 9.24 開催

日本咀嚼学会第28回学術大会

咀嚼機能検査用グミ「グルコラム」を用いた咀嚼試験

加藤伸一

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NEW

2017.9.9 〜 9.12 開催

AAP 103rd Annual Meeting

Detectability evaluation of novel DNA chip against periodontopathic bacteria

Natsuki Sasabe, Kazuto Takayama, Hijiri Masuda, Hiroki Naito, Yoko Ishihara, Hidetoshi Funabashi & Tomohiro Kumagai

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2017.6.8 〜 6.9 開催

日本歯科保存学会平成29年度春季大会(第146回)

DNAチップを用いた歯周病原細菌の検出能の評価

山和人、小田奈津季、船橋英利、熊谷知弘

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2017.5.12 〜 5.13 開催

第60回春季日本歯周病学会学術大会

DNAチップによる口腔内細菌叢解析と臨床所見の関連性評価

小田奈津季、山和人、船橋英利、熊谷知弘

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2016.7.8 〜 7.10 開催

日本補綴歯科学会第125回学術大会

成長過程における児童の最大舌圧と口腔・身体機能との関連

藤原茂弘、小野高裕、掘 一浩、山本雅章、田中佑人、來田百代、徳田佳嗣、菊井美希、
村上和裕、前田芳信、津賀一弘、増田裕次

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2011.09.15 発行

東京都歯科医師会雑誌 第59巻 第9号 2011年9月

先進医療に導入されたチェアサイドで簡便に行える咀嚼機能検査

志賀 博、小林義典

歯科臨床は、損なわれた咀嚼機能の回復とその維持を主な目的として標榜してきたが、肝心な咀嚼機能の診断は、一般に主観的または経験的な評価に拠っているのが現状である。もちろん、食品摂取のアンケート調査、咀嚼能力、咬合力、咬合接触面積、咀嚼筋筋活動、咀嚼運動などの分析が試みられ、少なからぬ成果も報告されているが、操作や分析の煩雑性、装置の経済性、あるいは分析の妥当性や信頼性の面などでさらなる検討の余地が残されている。

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2014.10.31 公開

日本歯科保存学雑誌vol.57(2014)No.5

A Three-year Follow-up Study for Levels of Salivary Streptococcus mutans and Streptococcus sobrinus from Japanese Adolescents by Quantitative Real-time PCR

Yoko Ishihara

Purpose: The purpose of this study was to investigate changes in Streptococcus mutans and Streptococcus sobrinus levels in saliva using TaqMan real-time PCR, once when the subjects were aged 12-13 years, and again 3 years later when the subjects were aged 15-16 years, in order to gain insights into caries prevention during adolescence.
Methods: The subjects were 88 Japanese adolescents (46 boys and 42 girls) in their first year of Tsurumi Junior High School in 2010, and in their first year of high school in 2013. Stimulated saliva was collected, and salivary S. mutans and S. sobrinus levels were obtained by real-time PCR. DMFT scores were also examined.
Results: Neither S. mutans nor S. sobrinus had formed colonies in 32 students (36.4%) at age 12-13 years, and remained undetected (<103 cells/ml) in 24 of these students (75%) 3 years later. These results suggested that individuals in whom S. mutans and S. sobrinus have not formed colonies by age 12-13 remained non-carriers (<103) for 3 years. In 9.1% of students, bacteria were detected in 2013 only, possibly due to horizontal transmission. In 5.7% of students, S. mutans and S. sobrinus were only detected in 2010, suggesting that transient flora had been detected. In 57.9% of students, bacteria were detected at both time points, indicating possible colonization. DMFT scores in S. mutans and S. sobrinus carriers tended to be higher than in non-carriers.
Conclusion: This study demonstrated the importance of inhibiting S. mutans and S. sobrinus colonization to prevent dental caries. As two or more bacterial tests must be conducted in order to determine S. mutans and S. sobrinus colonization, it is recommended that such bacterial tests be conducted at a dental clinic or during school health check-ups.

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